2CNF: Structural Insights Into The Design Of Nonpeptidic Isothiazolidinone- Containing Inhibitors Of Protein Tyrosine Phosphatase 1b

PDB ID: 2CNFDownload
MMDB ID: 41380
PDB Deposition Date: 2006/5/21
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 2CNF: monomeric; determined by author and by software (PQS)
Molecular Components in 2CNF
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Phosphatase Non-receptor Type 1
(Gene symbol: PTPN1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
(5s)-5-{4-[(2s)-2-(1h-Benzimidazol-2-Yl)-2-(1,3-Benzothiazol-2-Ylamino)ethyl]phenyl}isothiazolidin-3-One 1,1-Dioxide(5s)-5-{4-[(2s)-2-(1h-Benzimidazol-2-Yl)-2-(1,3-Benzothiazol-2-Ylamino)ethyl]phenyl}isothiazolidin-3-One 1,1-Dioxide
2
1
Magnesium IonMagnesium Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303